On this day, I loaded several wafers with drugs to test whether they would actually take to the wafers and what kind of stability the resulting product has. To do this, each wafer had its thickness measured at periodic intervals as the drugs were released in various pHs. The most important pHs to test are physiological pHs because these are the kinds of conditions the wafers would be exposed to in an actual application.
I also tested the spin coater to see how easily PGMA could be added to the wafer. Various rpms (rotation per minute) and rpm/s (rotation per minute per second) were tried out, but it was difficult to get a homogeneous layer. Instead, the wafer would be visibly covered in a non-uniform layer. However, rinsing the wafers in acetone would make this layer disappear.
Near the end of the day, I did some research on two possible drug candidates, polymyxin B and tobramycin, to see if they could be used for this application.
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